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TNS3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 20053-1-AP-20UL

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Product Code. 16899534

  • 1696.32 NOK / 20µL

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Description

Description

The antibody recognizes all isoforms of TNS3.

The Tensin (Tns) family of proteins is involved in the maintece of cellular structure by anchoring actin filaments at the focal adhesion via F-actin binding and capping activities. Tns proteins also contain a Src homology 2 (SH2) domain and have the ability to be phosphorylated, suggesting a role in signal transduction cascades. These diverse characteristics indicate that Tns proteins may be important links between the cytoskeleton and signal transduction pathways. Tns3, also known as TEM6 or TENS1, localizes to the focal adhesions of the plasma membrane. It is predomitly expressed in thyroid and placenta but can also be found in heart, liver, brain, prostate, pancreas, kidney, lung, skeletal muscle and white blood cells. Tns3 is essential for proper growth and development, as suggested by growth retardation and death in a number of Tns3-/- mice.
Specifications

Specifications

TNS3
Polyclonal
Unconjugated
TNS3
H_NH049I23.2, TEM6, TENS1, tensin 3, TNS3, TPP, Tumor endothelial marker 6
Rabbit
Antigen Affinity Chromatography
RUO
319939, 360980, 64759
-20°C
Liquid
Western Blot
0.3 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q5SSZ5, Q68CZ2
Tns3
Peptide
20 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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