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TLX1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand: Invitrogen PA534553

Product Code. 15305481

4060.00 NOK / 100µg

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Description

A suggested positive control is mouse spleen tissue lysate. PA5-34553 can be used with blocking peptide PEP-1596.

The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX1, also called homeobox11 (HOX11), as it is located outside of the four mammalian Hox clusters, is a DNA-binding nuclear transcription factor. TLX1 encodes a homeobox-domain containing protein and is containing a glycine and proline-rich amino terminus. TLX1 is required for maintenance of the developing spleen and cell survival. TLX1 is highly expressed in T-cell leukemia and lymphoid neoplasias as a result of translocation. TLX1-deficient mice have no spleen.

Specifications

Antigen	TLX1
Classification	Polyclonal
Conjugate	Unconjugated
Gene	TLX1
Gene Alias	homeo box-11 (T-cell leukemia-3 associated breakpoint, homologous to Drosophila Notch); homeobox protein Hox11; homeobox protein Hox-11; homeobox TLX-1; HOX11; Hox-11; LOW QUALITY PROTEIN: T-cell leukemia homeobox protein 1; MGC163402; proto-oncogene TCL-3; RGD1563655; SI:dZ46P4.1; T cell leukemia homeobox 1; T cell leukemia, homeobox 1; T-cell leukemia homeobox 1; T-cell leukemia homeobox protein 1; T-cell leukemia, homeobox 1; T-cell leukemia/lymphoma protein 3; TCL3; TLX1; Tlx-1; transcription factor; ztlx-1
Host Species	Rabbit
Purification Method	Antigen affinity chromatography
Regulatory Status	RUO
Gene ID (Entrez)	21908, 3195, 499361
Content And Storage	Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form	Liquid

Applications	Immunohistochemistry, Western Blot
Concentration	1 mg/mL
Formulation	PBS with 0.02% sodium azide
Gene Accession No.	P31314, P43345
Gene Symbols	TLX1
Immunogen	A 16 amino acid peptide near the amino terminus of human TLX1
Quantity	100 μg
Primary or Secondary	Primary
Target Species	Human, Mouse, Rat
Product Type	Antibody
Isotype	IgG

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TLX1 Polyclonal Antibody, Invitrogen™ > 100 μg; Unconjugated

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TLX1 Polyclonal Antibody, Invitrogen™

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