missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. STEMCELL Technologies SIS3
  6. 17130302

STEMCELL Technologies SIS3

Activin/NODAL/TGF-β pathway inhibitor; Inhibits SMAD3

Brand:  STEMCELL Technologies 73964

Encompass_Preferred

 View more versions of this product

Product Code. 17130302

  • 2237.52 NOK / 1mg

Please to purchase this item. Need a web account? Register with us today!

Explore more special offers
This item is not returnable. View return policy

Description

Description

  • SIS3 (specific inhibitor of SMAD3) is a cell-permeable selective inhibitor of transforming growth factor β1 (TGF-β1)-dependent SMAD3 phosphorylation (IC50 = 3 μM) and SMAD3-mediated cellular signaling (Jinnin et al.) SIS3 has no effect on SMAD2, p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase (ERK), or phosphoinositide 3-kinases
  • Facilitates the production of anterior ectoderm from mouse induced pluripotent stem cells (Oshima et al.)
  • Inhibits myofibroblast differentiation of normal human dermal fibroblasts (Jinnin et al.)
Specifications

Specifications

1009104-85-1
1 mg
≥98%
Smad3 inhibitor
C28H27N3O3
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.