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ROCK1 Antibody (154C1465) - (active/cleaved) - BSA Free, Novus Biologicals™
Mouse Monoclonal Antibody has been used in 5 publications
Brand: Novus Biologicals NB100-56596SS
This item is not returnable.
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Description
ROCK1 Monoclonal specifically detects ROCK1 in Human, Mouse, Rat, Canine, Primate, Rabbit samples. It is validated for Western Blot, Immunocytochemistry/Immunofluorescence.Specifications
| cleaved ROCK1 | |
| Monoclonal | |
| 0.5 mg/mL | |
| Western Blot 1-2 ug/ml, Immunocytochemistry/Immunofluorescence reported in scientific literature (PMID 21059388) | |
| EC 2.7.11, EC 2.7.11.1, MGC131603, MGC43611, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho kinase, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase 1 | |
| Mouse | |
| Protein G purified | |
| RUO | |
| Primary | |
| This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis. | |
| Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | |
| IgG |
| Western Blot, Immunocytochemistry, Immunofluorescence | |
| 154C1465 | |
| Unconjugated | |
| O60259 | |
| ROCK1 | |
| This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to amino acids 1114-1126 GNLPESRIEGWLS of human ROCK-1. This sequence is 100% conserved between human, chimpanzee, mouse, rat, dog, and rabbit. This immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1. | |
| 0.025 mg | |
| Apoptosis, Breast Cancer, Cancer, Signal Transduction, Wnt Signaling Pathway | |
| 6093 | |
| Human, Mouse, Rat, Canine, Primate, Rabbit | |
| Purified |
For Research Use Only