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Rad51D Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1696.32 NOK - 4796.50 NOK

Specifications

Antigen Rad51D
Concentration 0.21 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16847993
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Proteintech
11126-1-AP-20UL
20 μL
1696.32 NOK
20µL
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16837993
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Proteintech
11126-1-AP-150UL
150 μL
4796.50 NOK
150µL
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Description

Description

Rad52 family members (Rad50, Rad51B/C/D, Rad52, Rad54, MRE11) mediate DNA double-strand break repair (DSBR) for DNA damage that otherwise could cause cell death, mutation or neoplastic transformation. Rad51 (RECA, BRCC5) interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of Rad51. Rad52 forms a heptameric ring that binds single-stranded DNA ends and catalyzes DNA-DNA interaction necessary for the annealing of complementary strands. Rad52 can interact with Rad51. Rad54A of the DEAD-like helicase superfamily binds to double-strand DNA and induces a DNA topological change, which is thought to facilitate homologous DNA pairing and stimulate DNA recombination. Rad54B of the DEAD-like helicase superfamily binds to double-stranded DNA and displays ATPase activity in the presence of DNA. Rad54B is abundant in testis and spleen, and mutations of this gene occur in primary lymphoma and colon cancer
Specifications

Specifications

Rad51D
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Human, Mouse, Rat
O55230, O75771
19364, 303375, 5892
Rad51D Fusion Protein Ag1595
Primary
-20°C
RAD51D
0.21 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
HsTRAD, R51H3, RAD51 homolog D, RAD51 like 3 (S. cerevisiae), RAD51 like protein 3, Rad51D, RAD51L3, Trad
RAD51D
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

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