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Thermo Scientific™ Pierce™ Trifluoroacetic Acid (TFA), LC-MS Grade
Bottles of 99.5%-pure TFA (MW 114.02, CAS 76-05-01) liquid (sold by weight); for HPLC use as an ion-pairing agent in reverse-phase peptide separations.
Brand: Thermo Scientific™ 85183
Description
Thermo Scientific™ Pierce Trifluoroacetic Acid (TFA) is manufactured and tested to meet strict specifications that ensure superior performance for use as an ion-pairing agent in reverse-phase peptide separations.
For complex peptide separations, the key to success can be to vary selectivity. Varying mobile phase composition on the same column can change selectivity enough to resolve peptide that would otherwise overlap. The TFA concentration is usually specified as 0.1% for reverse-phase HPLC of peptides. For reproducible separations from run-to-run or from lab-to-lab, it is essential to make concentrations the same.
Highlights:
- Purity: >99.5% TFA and exceptional clarity allows sensitive, nondestructive peptide detection at low UV wavelengths
- High-performance packaging: Packaged under nitrogen in amber glass with protective TFE-lined fluorocarbon caps to ensure TFA integrity
- Choice of formats for convenience: 1mL ampules can prepare 1L of 0.1% v/v TFA solution for the mobile phase in reverse-phase chromatography in moments
Ordering Information:
X in the ordering table indicates that hazardous shipping charges apply.
Specifications
Trifluoroacetic Acid (TFA) | |
Liquid | |
50 mL | |
Pierce™ |
Store in a cool, dry, and well-ventilated area. Protect from direct sunlight. | |
Ion Pairing Reagent | |
99.5% TFA |
Safety and Handling
- Trifluoroacetic Acid
Signal Word
- Danger
Hazard Category
- Acute toxicity Category 3
- LONG-TERM AQUATIC HAZARD Chronic 3
- Skin corrosion/irritation Category 1 A
Hazard Statement
- H314-Causes severe skin burns and eye damage.
- H331-Toxic if inhaled.
- H412-Harmful to aquatic life with long lasting effects.
Precautionary Statement
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P405-Store locked up.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Supplemental information
- MIXTURE LIST-Contains : trifluoroacetic acid
For Research Use Only. Not for use in diagnostic procedures.