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Thermo Scientific™ Pierce™ Hydroxylamine-HCl

NH2OH (CAS 7803-49-8) to cleave Asn-Gly peptide bonds or deprotect sulfhydryls following S-acetylthioacetate modification with SATA reagent.

Brand:  Thermo Scientific™ 26103


Product Code. 11881405

  • 560.00 NOK / 25g

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Description

Description

Thermo Scientific™ Pierce Hydroxylamine-HCl has many uses, including to cleave Asn-Gly peptide bonds and to deprotect (expose) sulfhydryls for conjugation following modification with SATA and similar reagents.

Thermo Scientific™ Pierce Hydroxylamine-HCl has many uses, which include cleaving Asn-Gly peptide bonds and deprotecting (exposing) sulfhydryls on SATA-modified molecules for conjugation. Hydroxylamine·HCl is a strong reducing agent that is useful in biochemical crosslinking applications, including the deacetylation of SATA and chemical cleavage of EGS and Sulfo-EGS. Hydroxylamine converts carbonyl compounds (aldehydes and ketones) to their oxime derivatives in the presence of a weak base. Therefore, crosslinkers and other compounds that contain a carbonyl within their structure are cleavable with hydroxylamine-HCl.

Highlights:

  • Exposes protected sulfhydryl groups on SATA-modified molecules
  • Cleaves carbonyl-containing crosslinkers such as EGS

Reagent Properties:

  • Chemical name: Hydroxylamine Hydrochloride
  • Chemical formula: NH2OH·HCl
  • Molecular weight: 69.49
  • CAS Number: 5470-11-1
  • Form: White crystals, free of foreign material
  • Solubility: 10%
TRUSTED_SUSTAINABILITY
Specifications

Specifications

5470-11-1
Pierce™
SATA
Hydroxylamine Hydrochloride
Upon receipt store desiccated at room temperature. Product shipped at ambient temperature.
Solid
25 g
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Product Information

Manuals

User Guide: Hydroxylamine HCl Version: Jan. 2015 File size: 46.6 kB
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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberZJ398029 Certificate TypeCertificate of Analysis Date16/12/2024 Catalog Number26103
Lot NumberZH387831 Certificate TypeCertificate of Analysis Date15/10/2024 Catalog Number26103
Lot NumberZF385875 Certificate TypeCertificate of Analysis Date11/07/2024 Catalog Number26103
Lot NumberZC379384 Certificate TypeCertificate of Analysis Date14/04/2024 Catalog Number26103
Lot NumberZA379383 Certificate TypeCertificate of Analysis Date25/01/2024 Catalog Number26103
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For Research Use Only. Not for use in diagnostic procedures.