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PF 04457845
Potent and selective irreversible FAAH inhibitor
Brand: Tocris Bioscience 6374/5
1002.14 NOK valid until 2024-12-16
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Description
PF 04457845 is a potent and selective irreversible FAAH inhibitor (IC50 = 7.2 nM, which is selective for FAAH over a panel of other serine hydrolases. PF 04457845 exhibits efficacy in a rat inflammatory pain model, and is orally bioavailable and brain penetrant.Specifications
| N-3-Pyridazinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methylene]-1-piperidinecarboxamide | |
| >98% | |
| C23H20F3N5O2 |
| 1020315-31-4 | |
| 5 mg | |
| Observed MW: 455.43 |