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  6. 18768347

Tocris Bioscience™ JIB 04

Pan Jumonji inhibitor; active in vivo

Brand:  Tocris Bioscience™ 4972/50

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Product Code. 18768347

  • 9800.00 NOK / 50mg

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Description

Description

JIB 04 is a pan Jumonji histone demethylase inhibitor (IC50 values are 230, 340, 435, 445, 855 and 1100 nM for JARID1A, JMJD2E, JMJD2B, JMJD2A, JMJD3 and JMJD2C respectively). Exhibits negligible activity at PHD2 and TET1. Selectively blocks cancer cell growth in vitro and diminishes tumor growth in H358 and A549 mouse xenograft models in vivo. Prolongs survival in a mouse model of breast cancer.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

>99%
JIB 04
JIB 04
50 mg
308.76
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