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Tocris Bioscience™ JIB 04
Pan Jumonji inhibitor; active in vivo
Brand: Tocris Bioscience™ 4972/50
7754.44 NOK valid until 2024-12-16
Use promo code "21630" to get your promotional price.
This item is not returnable.
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Description
JIB 04 is a pan Jumonji histone demethylase inhibitor (IC50 values are 230, 340, 435, 445, 855 and 1100 nM for JARID1A, JMJD2E, JMJD2B, JMJD2A, JMJD3 and JMJD2C respectively). Exhibits negligible activity at PHD2 and TET1. Selectively blocks cancer cell growth in vitro and diminishes tumor growth in H358 and A549 mouse xenograft models in vivo. Prolongs survival in a mouse model of breast cancer.Specifications
| >99% | |
| JIB 04 | |
| JIB 04 |
| 50 mg | |
| 308.76 |
For Research Use Only