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  6. CD157 Monoclonal Antibody (eBioSY11B5 (SY11B5)), eBioscience™, Invitrogen™
  7. 17110582

CD157 Monoclonal Antibody (eBioSY11B5 (SY11B5)), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1579-95

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Product Code. 17110582

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Description

Description

The eBioSY11B5 MAb recognizes human CD157 (Mo5, BST-1). CD157 is a 42-45 kDa, GPI-anchored protein with structural and functional similarities with CD38. CD157 was initially cloned because of its expression on monocytes and macrophages, and was subsequently discovered to be the same protein named BST-1, discovered for its expression on bone marrow stromal cells and its ability to stimulate the proliferation of a mouse pre-B cell line. CD157 is a pleiotropic ectoenzyme and is thought to act independently as an enzyme and receptor. Similar to CD38, CD157 is involved in the metabolism of NAD+ and this activity may be involved in regulating intracellular Ca2+ levels. As a receptor, upon binding of its putative ligand, CD157 is thought to initiate a signal transduction cascade resulting in the phosphorylation of cytoplasmic proteins including focal adhesion kinase (FAK). The mechanism and functional significance of CD157-initiated signal transduction remain to be fully characterized.

CD157 Monoclonal antibody specifically detects CD157 in Human samples. It is validated for Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
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Specifications

Specifications

CD157
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q10588
Mouse
10 mg
Primary
Human
Antibody
IgG1 κ
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
eBioSY11B5 (SY11B5)
Unconjugated
Bst1
114/A10; A530073F09; ADP-ribosyl cyclase 2; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; Antigen BP3; bone marrow stromal antigen 1; bone marrow stromal cell antigen 1; Bp3; Bp-3; BP-3 alloantigen; BST1; BST-1; Bsta1; cADPr hydrolase 2; CD157; CD157 antigen; Cyclic ADP-ribose hydrolase 2; leukocyte antigen 65; Ly65; Ly-65; NAD(+) nucleosidase; NAD+ nucleosidase
Affinity chromatography
RUO
683
4° C
Liquid
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