General Cell Based Assays
General Cell Based Assays
Thermo Scientific™ Kinase Tracer 236, 50 μM
In the LanthaScreenâ„¢ Eu Kinase Binding Assay, binding of an Alexa Fluorâ„¢ conjugate or tracer such as Kinase Tracer 236 to a kinase is detected by addition of a Eu-labeled anti-tag antibody.
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Thermo Scientificâ„¢ Tangoâ„¢ AGTRL1-bla U2OS Cells
The Tangoâ„¢ AGTRL1-bla U2OS cells contain the human Angtiotension-Like Receptor 1 (AGTRL1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tangoâ„¢ GPCR-bla U2OS parental cell line.
Thermo Scientificâ„¢ LanthaScreenâ„¢ STAT1 U2OS Cell Line
The JAK/STAT1 signaling pathway is known to be activated by type I/II interferons such as interferon-gamma and interferon-alpha.
Thermo Scientificâ„¢ CellSensorâ„¢ CRE-bla Jurkat Cell Line
The CRE-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into Jurkat cells.
Thermo Scientificâ„¢ LanthaScreenâ„¢ STAT5 TF-1 Cell Line
LanthaScreenâ„¢ GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context.
Thermo Scientificâ„¢ CellSensorâ„¢ TrkA-NFAT-bla CHO-K1 Cell Line
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death.
Invitrogenâ„¢ BacMam LRRK2-GFP G2019S Reagent
BacMam LRRK2-GFP G2019S Reagent is a modified insect cell virus (baculovirus) that enables easy, efficient, and titratable overexpression of full-length LRRK2-GFP G2019S in your choice of cellular background, including primary neurons and neuroblastoma cell lines.
Thermo Scientificâ„¢ CellSensorâ„¢ AP-1-bla HEK293T Cell Line
The CellSensorâ„¢ AP-1-bla HEK 293T Cell Line contains a beta-lactamase reporter gene under control of the AP-1 response element stably integrated into HEK 293T cells.
Thermo Scientificâ„¢ GeneBLAzerâ„¢ MC2R CHO-K1 DA Assay Kit
The GeneBLAzerâ„¢ MC2R CHO-K1 DA (Division Arrested) cells contain the human melanocortin-2 receptor (MC2R), and the Melanocortin-2 receptor accessory protein (MRAP), stably integrated into the CellSensorâ„¢ CRE-bla CHO-K1 cell line.
Thermo Scientificâ„¢ GeneBLAzerâ„¢ PPAR delta DA Assay Kit
GeneBLAzerâ„¢ PPAR delta DA (Division Arrested) cells and PPAR delta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Peroxisome Proliferator-Activated Receptor-delta (PPAR delta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzerâ„¢ UAS-bla HEK 293T cell line.
Thermo Scientificâ„¢ CellSensorâ„¢ irf1-bla TF-1 Cell Line
Jak/Stat signaling pathways play essential roles in cellular responses to distinct cytokines. One of the Jak/Stat pathways, Jak2/Stat5, mediates cell proliferation in response to Interleukin-3 (IL-3), prolactin, erythropoietin (Epo), and granulocyte-macrophage colony stimulating factor (GM-CSF).
Thermo Scientificâ„¢ GeneBLAzerâ„¢ GPR24-Gqi5-NFAT-bla CHO-K1 Cells
GeneBLAzerâ„¢ GPR24-Gqi5-NFAT-bla CHO-K1 cells contain the human Melanin-concetrating hormone receptor (GPR24) stably integrated into the GeneBLAzerâ„¢ Gqi5-NFAT-bla CHO-K1 cell line.
Thermo Scientificâ„¢ Tangoâ„¢ SSTR1-bla U2OS Cells
The Tangoâ„¢ SSTR1-bla U2OS cells contain the human Somatostatin Receptor 1 (SSTR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tangoâ„¢ GPCR-bla U2OS parental cell line.
Thermo Scientificâ„¢ GeneBLAzerâ„¢ MC5R-CRE-bla CHO-K1 Cells
GeneBLAzerâ„¢ MC5R-CRE-bla CHO-K1 cells contain the human Melanocortin Receptor 5 (MC5R) stably integrated into the CellSensorâ„¢ CRE-bla CHO-K1 cell line.
Thermo Scientificâ„¢ CellSensorâ„¢ ISRE-bla HEK293T Cell Line
The CellSensorâ„¢ ISRE-bla HEK 293T cell line is responsive to interferon alpha and can be used to probe the JAK/STAT signaling pathway.