The CellSensor™ AP-1-bla HEK 293T Cell Line contains a beta-lactamase reporter gene under control of the AP-1 response element stably integrated into HEK 293T cells.
Brand: Thermo Scientific™ K1658
The CellSensor™ AP-1-bla HEK 293T Cell Line contains a beta-lactamase reporter gene under control of the AP-1 response element stably integrated into HEK 293T cells. The cell line was created through sorting by FACS of cells responsive to stimulation of the AP-1 pathway with phorbol 12-myristate 13-acetate (PMA). The cell line was validated for DMSO tolerance, incubation time with stimulant, and substrate loading conditions. The AP-1-bla HEK 293T cell line responds to agonist treatment as expected from literature and can be adapted for high throughput screening for agonists or antagonists of the AP-1 pathway with compound libraries. Candidate drugs can also be tested for dose response against this cell line. Academic and non-profit customers, please inquire for special pricing.
| Cell-based beta lactamase reporter gene | |
| CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use. | |
| Fluorescent | |
| beta-lactamase reporter gene under control of the AP-1 response element stably integrated into HEK 293T cells | |
| 1 Vial | |
| EGFR, ERK1/2, p38, MEK, MAPK pathway, c-MET, JNK, RON, RAF | |
| CellSensor™ |
| Dividing Cells | |
| CellSensor™ AP-1-bla HEK293T Cell Line, 1Vial, ∽2,000,000 cells/vial at 2,000,000 cells/mL Quantity of Cells, AP-1-bla HEK293T Cell Line, Fluorescent Detection Method, CellSensor™ Druggable Target, Adherent Growth Properties, Liquid Nitrogen Storage | |
| Pharma and biopharma, drug discovery and development, target and lead identification and validation, pathway biology, cellular pathway analysis assays, cellsensor™ cellular pathway assays | |
| CellSensor™ | |
| AP-1-bla HEK293T | |
| Cell Line | |
| Signaling Pathway |
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For Research Use Only. Not for use in diagnostic procedures.
