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Tocris Bioscience™ VU 0546110

Selective SLO3 potassium channel inhibitor

Brand:  Tocris Bioscience™ 7956/10

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Product Code. 18015852

  • 1475.00 NOK / 10mg

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Description

Description

VU 0546110 is a selective inhibitor of the sperm-specific potassium channel SLO3 (IC50 = 64 μM). It shows 40-fold selectivity over SLO1. It completely blocks heterologous SLO3 currents and endogenous K+ currents. VU 0546110 inhibits sperm hyperpolarisation and prevents its hyperactivated mobility.
Specifications

Specifications

1-[4-[[(4-Methoxyphenyl)thio]methyl]-1-piperidinyl]-2-[4-[(1-methylethyl)sulfonyl]phenyl]ethanone
10 mg
C24H31NO4S2
1421523-00-3
Non-selective/Other Potassium Channel Blockers
0.98
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