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TrkA Monoclonal Antibody (6B2), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA515509
3174.50 NOK valid until 2025-03-16
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Description
MA5-15509 targets TrkA in indirect ELISA, IF and WB applications and shows reactivity with Human samples. The MA5-15509 immunogen is purified recombinant extracellular fragment of human TrkA (aa33-423) fused with hIgGFc tag expressed in HEK293 cell line. MA5-15509 detects TrkA which has a predicted molecular weight of approximately 87.4kDa.
NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
Specifications
| TrkA | |
| Monoclonal | |
| Conc. Not Determined | |
| ascites with 0.03% sodium azide | |
| P04629 | |
| Ntrk1 | |
| Purified recombinant extracellular fragment of human TrkA (aa33-423) fused with hIgGFc tag expressed in HEK293 cell line. | |
| RUO | |
| 4914 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA, Immunocytochemistry, Western Blot | |
| 6B2 | |
| Unconjugated | |
| Ntrk1 | |
| C80751; DKFZp781I14186; EC 2.7.10.1; gp140trk; high affinity nerve growth factor receptor; kinase TrkA; MTC; neurotrophic receptor tyrosine kinase 1; Neurotrophic tyrosine kinase receptor type 1; neurotrophic tyrosine kinase, receptor, type 1; Ntrk1; Oncogene TRK; p140-TrkA; Slow nerve growth factor receptor; Tkr; TRK; TRK1; TRK1-transforming tyrosine kinase protein; Trka; Trk-A; TrkA neurotrophin receptor; trkA proto-oncogene receptor; tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A | |
| Mouse | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
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Product Title
TrkA Monoclonal Antibody (6B2), Invitrogen™ > 100 μL; Unconjugated
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