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Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water, Thermo Scientific Chemicals
Description
Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.
Solubility
Miscible with water and methanol.
Notes
Air sensitive. Store in cool place. Incompatible with strong oxidizing agents
Specifications
Specifications
| Linear Formula | (HO2CCH2CH2)3P·HCl |
| Quantity | 25 mL |
| UN Number | UN3265 |
| Solubility Information | Miscible with water and methanol. |
| Formula Weight | 286.65 |
| Percent Purity | 95% |
| Concentration or Composition (by Analyte or Components) | 0.5M soln. in water |
| Chemical Name or Material | Tris(2-carboxyethyl)phosphine hydrochloride |
Safety and Handling
- Tris(2-carboxyethyl)phosphine hydrochloride 0.5M aqueous solution
- Danger
- Serious eye damage/eye irritation Category 1
- Skin corrosion/irritation Category 1 B
- H314-Causes severe skin burns and eye damage.
- H318-Causes serious eye damage.
- H400-Very toxic to aquatic life.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
- MIXTURE LIST-Contains : Tris(2-carboxyethyl)phosphonium chloride
RUO – Research Use Only