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Trifluoroacetic acid, 99% Product Code.: 11424863
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Trifluoroacetic acid, 99%

Product Code. 11424863
2500 g, 2500g
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Product Code. 11424863

Brand: Thermo Scientific Alfa Aesar A12198.0E

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Description

Solvent, catalyst, strong non-oxidizing acid | CAS: 76-05-1 | C2HF3O2 | 114.02 g/mol

The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

Solubility
Miscible with ether, acetone, ethanol, benzene, hexane, and CCl4

Notes
Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.

Chemical Identifiers

CAS 76-05-1
Molecular Formula C2HF3O2
Molecular Weight (g/mol) 114.02
MDL Number MFCD00004169
InChI Key DTQVDTLACAAQTR-UHFFFAOYSA-N
Synonym trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoroacetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctovaShow MoreShow Less
PubChem CID 6422
ChEBI CHEBI:45892
IUPAC Name trifluoroacetic acid
SMILES OC(=O)C(F)(F)F

Specifications

Melting Point °C to 15°C
Boiling Point 72°C to 73°C
Assay Percent Range 99%
Beilstein 742035
Solubility Information Miscible with ether,acetone,ethanol,benzene,hexane,and CCl4
Formula Weight 114.02
Density 1.480
Quantity 2500 g
Physical Form Liquid
Refractive Index 1.284
Sensitivity Hygroscopic
Chemical Name or Material Trifluoroacetic Acid
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5 results found
Lot Number Certificate Type Date Product Code
Lot NumberA0470765 Certificate TypeCertificate of Analysis Date17/05/2025 Product CodeA12198.0E,A12198.22,A12198.36
Lot NumberM31L001 Certificate TypeCertificate of Analysis Date03/02/2025 Product CodeA12198.0E,A12198.22,A12198.36
Lot NumberY27K029 Certificate TypeCertificate of Analysis Date16/12/2024 Product CodeA12198.0E,A12198.22,A12198.36
Lot NumberX11K033 Certificate TypeCertificate of Analysis Date25/10/2024 Product CodeA12198.0E,A12198.22,A12198.36
Lot NumberX16K043 Certificate TypeCertificate of Analysis Date25/10/2024 Product CodeA12198.0E,A12198.22,A12198.36

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