Tocris Bioscience™ Gastrin I (human)

Description

Gastrin I (human) is an endogenous peptide produced in the stomach that acts as a selective CCK2 receptor agonist. Gastrin I stimulates gastric acid secretion and has a mitogenic effect on gastric cells. Gastrin stimulates gastric epithelial cell proliferation and histamine secretion (EC50 values are 6.2 pM and 0.014 nM, respectively). Gastrin I is also used in the culture of stomach, intestine and pancreas organoids. For more information about using Gastrin I in the generation of gastric organoids see the Human Gastric Organoid Culture Protocol .