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Thermo Scientific™ TheraPure™ Bz dA Phosphoramidite
TheraPure™ Bz dA Phosphoramidite is a phosphoramidite containing 5' DMT and the nucleoside deoxyadenosine (dA) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis.
Brand: Thermo Scientific™ 27-2030-75
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Description
- Bz-dA CEP is a phosphoramidite containing 5′ DMT and the nucleoside deoxyadenosine (dA) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis.
- DNA phosphoramidites are the building blocks for synthesis of DNA or DNA containing oligonucleotides.
- Each base has unique protecting groups designed specifically to protect the DNA during the chemical synthesis process, and produce the highest amount of full length product.
- Alternative protecting groups on dC (acetyl) and dG (DMF) allow for a faster deprotection of the oligonucleotide.
- The TheraPure trademark denotes a highest level of phosphoramidite purity, developed with the highest stringency of of high definiteion analytics and tightly controlled impurity profiles. Ideal for any therapeutic application.
- Features:
- Full chemical name: 5′-O-(4,4′-Dimethoxytrityl)-N6-benzoyl-2′-deoxyadenosine-3′-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
- Molecular formula: C47H52N7O7P
- Base: dA
- Base Protection: Bz
- Formula weight: 857.95 g/mol
- CAS number: 98796-53-3
- HPLC Purity: ≥99%; M-11 Impurity ≤0.01%; Single critical impurity ≤0.3%; Presence of dC, dG, or T impurity ≤0.03%
- 31P NMR Purity: ≥99%; Sum of non-primary peaks at 140-152 ppm: ≤0.3%; No peak(s) above 170 ppm; HMT impurity (∼146ppm): ≤0.10%
Specifications
| 5′-O-(4,4′-Dimethoxytrityl)-N6-benzoyl-2′-deoxyadenosine-3′-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | |
| 857.95 g/mol | |
| ≥99% | |
| 100 g |
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