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TCF3 Monoclonal Antibody (6B8), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA515603
2990.14 NOK valid until 2025-03-29
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Description
MA5-15603 targets TCF3 in indirect ELISA, FACS and WB applications and shows reactivity with Human samples. The MA5-15603 immunogen is purified recombinant fragment of human TCF3 expressed in E. Coli. MA5-15603 detects TCF3 which has a predicted molecular weight of approximately 67.6kDa.
TCF3 (E2A) is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.
Specifications
TCF3 | |
Monoclonal | |
Conc. Not Determined | |
ascites with 0.03% sodium azide | |
P15923 | |
TCF3 | |
Purified recombinant fragment of human TCF3 expressed in E. Coli. | |
RUO | |
6929 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
ELISA, Flow Cytometry, Western Blot | |
6B8 | |
Unconjugated | |
TCF3 | |
A1; AA408400; AGM8; Alf2; AW209082; bHLHb21; class B basic helix-loop-helix protein 21; E12; E12/E47; E2A; E47; helix-loop-helix protein HE47; immunoglobulin enhancer-binding factor E12/E47; Immunoglobulin transcription factor 1; ITF1; Kappa-E2-binding factor; Me2; MGC129647; MGC129648; negative vitamin D response element-binding protein; NOL1-TCF3 fusion; Pan; Pan1; Pan2; pancreas specific transcription factor 1c; Ptf1c; TCF3; TCF-3; Tcfe2a; Transcription factor 3; transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); transcription factor 3 variant 3; transcription factor A1; transcription factor E2a; Transcription factor E2-alpha; transcription factor ITF-1; Transcription regulator Pan; VDIR; VDR interacting repressor; vitamin D receptor-interacting repressor | |
Mouse | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
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