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TC E3 5031, Tocris Bioscience™
Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs
Brand: Tocris Bioscience 6466/100
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Description
TC E3 5031 is a derivative of Thalidomide (Cat.No. 0652), commonly used as a precursor to PROTAC® that hijacks cereblon as the E3 ubiquitin ligase component. Supplied with a carboxylic acid functional handle at a position known not to significantly affect binding to cereblon, for ready conjugation to a linker/target protein ligand.PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
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Specifications
| 1061605-21-7 | |
| 2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetic acid | |
| 100 mg |