Learn More
Thermo Scientific™ Tango™ NPY2R-bla U2OS Cells
The Tango™ NPY2R-bla U2OS cells contain the human Neuropeptide Y Receptor Y2 (NPY2R) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Brand: Thermo Scientific™ K1479
Description
The Tango™ NPY2R-bla U2OS cells contain the human Neuropeptide Y Receptor Y2 (NPY2R) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.
The Tango™ NPY2R-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of Neuropeptide Y. In addition, Tango™ NPY2R-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.

Specifications
NM_000910.2 | |
Dividing Cells | |
Tail from GRPR GPCR | |
Fluorescence | |
NPY2R | |
Pool of Stable Cells | |
2 x 106 Cells | |
U2OS | |
NPY2R | |
U2OS | |
GPCR |
Cell-based beta-arrestin recruitment | |
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol. Includes: • Tango™ NPY2R-bla U2OS cells • Tango™ NPY2R-bla U2OS Assay Protocol • Certificate of Analysis The Tango™ NPY2R-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt. |
|
Tango™ NPY2R-bla U2OS Cells, 2 x 106 Cells, ∽2,000,000 cells/vial at 2,000,000cells/mL Quantity of Cells, U2OS Cell Line, Fluorescent Detection Method, GPCRs Druggable Target, BLA (Beta-Lactamase) Reporter, Liquid Nitrogen Storage | |
Pharma and biopharma, drug discovery and development, target and lead identification and validation, G-protein coupled receptor biology, cell-based GPCR reporter assays | |
Tango™ NPY2R-bla U2OS cells (LiveBLAzer™-FRET B/G loading kit, solution D and other materials are required separately; please refer to the protocol). Includes: Tango™ NPY2R-bla U2OS cells, Tango™ NPY2R-bla U2OS assay protocol, certificate of analysis | |
Tango™ | |
BLA (Beta-Lactamase) | |
Room Temperature | |
U2OS Cell | |
Tango™ |
Certificates
A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.
Lot Number | Certificate Type | Date | Catalog Number |
---|---|---|---|
40442 | Certificate of Analysis | 16/04/2017 | K1479 |
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
For Research Use Only. Not for use in diagnostic procedures.