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STRADB Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10688-1-AP-150UL

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Product Code. 16847233

  • 4796.50 NOK / 150µL

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Description

Description

This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene.
Specifications

Specifications

STRADB
Polyclonal
Unconjugated
STRADB
ALS2CR2, CALS 21, ILP interacting protein, ILPIP, ILPIPA, PAPK, PRO1038, Pseudokinase ALS2CR2, STRAD beta, STRADB
Rabbit
Antigen Affinity Chromatography
RUO
227154, 501146, 55437
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.22 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8K4T3, Q9C0K7
STRADB
STRADB Fusion Protein Ag1040
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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