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Staurosporine, 99+%, Thermo Scientific Chemicals
Staurosporine (staurosporin, CAS # 62996-74-1) is a bacterial alkyloid isolated from Streptomyces staurosporeus.
1840.00 NOK - 11475.00 NOK
Chemical Identifiers
| CAS | 62996-74-1 |
|---|---|
| Molecular Formula | C28H26N4O3 |
| Molecular Weight (g/mol) | 466.541 |
| MDL Number | MFCD00077402 |
| InChI Key | HKSZLNNOFSGOKW-ZYSRIHRCSA-N |
| Synonym | Antibiotic AM-2282 |
| PubChem CID | 49831000 |
| SMILES | CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15495139
|
Thermo Scientific Alfa Aesar
J62837.M^ |
1 mg |
1840.00 NOK
1mg |
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|
15485139
|
Thermo Scientific Alfa Aesar
J62837.#0 |
5 mg |
6275.00 NOK
5mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
|
15405149
|
Thermo Scientific Alfa Aesar
J62837.MA |
10 mg |
11475.00 NOK
10mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Broad spectrum protein kinase inhibitor Staurosporine is used as anti-fungal and anti-hypertensive, which results to study the anti-cancer treatment. It acts as a precursor to protein kinase inhibitor midostaurin. It is also used to induce cell death in Swiss Webster primary macrophage cells and to study the effect of caspase activation on human sperm quality.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Staurosporine is an indolocarbazole alkaloid capable of permeating cell membranes
- Staurosporine has anti-cancer properties that can induce apoptosis
- Staurosporine is a broad inhibitor of protein kinases, preventing growth and division cycles
Application
- Staurosporine is used for research on acute myeloid leukemia
- It is suitable for research applications including cell culture and biochemistry
Chemical Identifiers
| 62996-74-1 | |
| 466.541 | |
| HKSZLNNOFSGOKW-ZYSRIHRCSA-N | |
| 49831000 |
| C28H26N4O3 | |
| MFCD00077402 | |
| Antibiotic AM-2282 | |
| CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC |
Specifications
| Staurosporine | |
| 62996-74-1 | |
| Yellow | |
| MFCD00077402 | |
| 14,8802 | |
| Soluble in DMSO or ethanol;Soluble in dimethyl sulfoxide ,dimethyl formamide,ethyl acetate,hot acetone and ethanol; Slightly soluble in chloroform and methanol; Insoluble in water. | |
| CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC | |
| 49831000 | |
| ≥99% |
| Powder | |
| 240°C to 243°C | |
| C28H26N4O3 | |
| 1060573 | |
| Antibiotic AM-2282 | |
| HKSZLNNOFSGOKW-ZYSRIHRCSA-N | |
| 466.541 | |
| 466.54 | |
| Staurosporine |
Safety and Handling
GHS H Statement
H350
May cause cancer.
P201-P202-P280-P308+P313-P501c
H351
missing translation for 'rtecsNumber' : KD5084000
missing translation for 'tsca' : No
missing translation for 'storageNote' : -30° to -10°C
Recommended Storage : Store at -20°C
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
- Staurosporine
Signal Word
- Warning
Hazard Category
- Carcinogenicity Category 2
Hazard Statement
- H351-Suspected of causing cancer.
Precautionary Statement
- P201-Obtain special instructions before use.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P308+P313-IF exposed or concerned: Get medical advice/attention.
RUO – Research Use Only
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Product Title
Staurosporine, 99+%, Thermo Scientific Chemicals