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SPDP, MedChemExpress Product Code.: 16439506
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SPDP, MedChemExpress

Product Code. 16439506
50 mg, 50mg
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Product Code. 16439506

Brand: Medchem Express HY100216

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Description

MedChemExpress SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).

SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).

Specifications

Chemical Name or Material SPDP
CAS 68181-17-9
Color White
Purity Grade Notes Research
Molecular Formula C12H12N2O4S2
Quantity 50 mg
Synonym SPDP Crosslinker
Solubility Information DMSO : 155 mg/mL (496.22 mM; Need ultrasonic)
SMILES O=C(ON1C(CCC1=O)=O)CCSSC2=NC=CC=C2
Molecular Weight (g/mol) 312.36
Formula Weight 312.36
Percent Purity 97.0%
Grade Research
Physical Form Solid
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Research purposes only

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