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Tocris Bioscience™ SN 38 Product Code.: 18782664

Tocris Bioscience™ SN 38
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Product Code. 18782664
10 mg, 10mg
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18782664

Brand: Tocris Bioscience™ 2684/10

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This item is not returnable. View return policy

DNA topoisomerase I inhibitor; antitumor

Active metabolite of CPT-11 (Cat. No. 2688) that inhibits DNA topoisomerase I (IC50 values are 0.74 and 1.9 ÎĽM in P388 and Ehrlich cells respectively). Inhibits DNA and RNA synthesis (IC50 values are 0.077 and 1.3 ÎĽM respectively) but does not affect protein synthesis. Displays potent antitumor activity against a range of human tumor cell lines (IC50 values are 3.3, 13, 19 and 22 nM for HCT-116, BEL-7402, HL60 and HELA cells respectively).
Greener Choice Claims
  • Environmental benefits include:
    • Ozone-Safe or Safe for the Ozone Layer
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 86639-52-3
Molecular Formula C22H20N2O5
Molecular Weight (g/mol) 392.411

Specifications

Quantity 10 mg
Formula Weight 392.4
Purity >98%
Chemical Name or Material SN 38
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