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SAHA, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
SAHA inhibits Class I and II histone deacetylases (HDACs); induces accumulation of acetylated histones H2A, H2B, H3 and H4 in transformed cultured cells. Suppresses cell growth in a range of cancer cell lines; induces apoptosis in cutaneous T cell lymphoma cells in vitro. Activates autophagy. SAHA increases efficiency of transcription factor-induced reprogramming of mouse embryonic fibroblasts (MEF) to induced pluripotent stem cells (iPSC). Also enhances adeno-associated virus transduction of HeLa cells.
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Specifications
Specifications
Quantity | 10 mg |
Formula Weight | 264.32 |
Percent Purity | >98% |
Chemical Name or Material | SAHA |
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