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Ribavirin, Tocris Bioscience™
GREENER_CHOICE

Serine protease inhibitor; inhibits tryptase

Brand:  Tocris Bioscience 4501/50

Quantity 50 mg

Product Code. 30001509

  • 1775.00 NOK / 10mg

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Description

Description

Antiviral guanosine ribonucleoside analog; misincorporated into mRNA by viral-dependent RNA polymerases. Binds to and redistributes mammalian eIF4E from the nucleus to the cytoplasm (Ki ∽ 0.3 μM for the active metabolite, ribavirin triphosphate). Also inosine monophosphate dehydrogenase (IMPDH) inhibitor. Represses colony formation of primary AML-M5 progenitor cells (IC50 ∽ 1 μM); reduces disease severity in acute myeloid leukemia (AML). Inhibits cytopathic effect of SARS-CoV in Vero cells in vitro. Orally available.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

36791-04-5
50 mg
IWUCXVSUMQZMFG-AFCXAGJDSA-N
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
37542
244.2
Protein-synthesizing GTPase Compounds
C8H12N4O5
ribavirin, tribavirin, virazole, rebetol, ribavirine, copegus, vilona, ribamide, ribamidil, ribasphere
C1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
244.207
CHEBI:63580
>99%
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