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Raloxifene hydrochloride, Tocris Bioscience™

Product Code. 18752584
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Quantity:
50 mg
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This item is not returnable. View return policy

Description

Selective estrogen receptor modulator (SERM)

Selective estrogen receptor modulator (SERM) that binds to ERα and ERβ, and tissue-dependently activates or blocks estrogen-induced transcription. Acts as an antiestrogen in breast and uterine tissue, but displays estrogen agonist activity in bone. In D12 rat hypothalamic cells, inhibits progesterone receptor induction by estrogen with an IC50 of 1 nM.

Specifications

CAS 82640-04-8
Molecular Formula C28H28ClNO4S
Quantity 50 mg
Synonym raloxifene hydrochloride, raloxifene hcl, evista, keoxifene hydrochloride, 6-hydroxy-2-4-hydroxyphenyl benzo b thiophen-3-yl 4-2-piperidin-1-yl ethoxy phenyl methanone hydrochloride, keoxifene, unii-4f86w47br6, evista raloxifene hydrochloride, 6-hydroxy-2-p-hydroxyphenyl benzo b thien-3-yl-p-2-piperidinoethoxy phenyl ketone, hydrochloride
InChI Key BKXVVCILCIUCLG-UHFFFAOYSA-N
SMILES C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O.Cl
IUPAC Name [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone;hydrochloride
Molecular Weight (g/mol) 510.045
PubChem CID 54900
ChEBI CHEBI:50740
Formula Weight 510.04
Percent Purity >98%
Chemical Name or Material Raloxifene hydrochloride
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