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Tocris Bioscience™ Pyr 10

Selective TRPC3 inhibitor

Brand: Tocris Bioscience™ 6941/50

5796.82 NOK valid until 2024-12-16
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Product Code. 18768946

7330.00 NOK / 50mg

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Description

Pyr 10 is a TRPC3 (transient receptor potential canonical 3) channel inhibitor (IC50 = 0.72 μM for TRPC3 mediated calcium entry in vitro), which displays approximately 18-fold selectivity for TRPC3-mediated receptor operated calcium entry (ROCE) over STIM1/Orai1-mediated store operated calcium entry (SOCE). Pyr 10 inhibits NFATc3 activation and inhibits proliferation of rat ventricular cardiac fibroblasts.

Specifications

Chemical Name or Material	N-[4-[3,5-bis(Trifluoromethyl)-1 H-pyrazol-1-yl]phenyl]-4-methylbenzenesulfonamide
Quantity	50 mg
Molecular Formula	C₁₈H₁₃F₆N₃O₂S

CAS	1315323-00-2
Target	TRPC Channel Blockers
Purity	0.98

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