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PYGL Mouse anti-Human, Clone: 1G12D8, Proteintech
Mouse Monoclonal Antibody
1611.84 NOK - 4593.76 NOK
Specifications
Antigen | PYGL |
---|---|
Clone | 1G12D8 |
Concentration | 1 mg/mL |
Applications | Western Blot |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16808955
|
Proteintech
66769-1-IG-20UL |
20 μL |
1611.84 NOK
20µL |
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16898945
|
Proteintech
66769-1-IG-150UL |
150 μL |
4593.76 NOK
150µL |
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Description
This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues. In glycogen storage disease type VI, also known as Hers disease, mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia, mild ketosis, growth retardation and hepatomegaly. Alternative splicing results in multiple transcript variants encoding different isoforms.Specifications
PYGL | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
GSD6, phosphorylase, glycogen, liver, PYGL | |
PYGL | |
IgG1 | |
Protein G | |
Antibody |
1G12D8 | |
Western Blot | |
Unconjugated | |
Mouse | |
Human | |
P06737 | |
5836 | |
PYGL Fusion Protein Ag8550 | |
Primary | |
-20°C | |
PYGL |