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Tocris Bioscience™ Pregnenolone sulfate sodium salt
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NMDA potentiator; also GABAA inhibitor and TRPM3 activator

Brand:  Tocris Bioscience™ 5376/50

Encompass

Product Code. 15737356

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Description

Description

Pregnenolone sulfate sodium salt is a highly potent neurosteroid with multiple actions. Enhances intracellular Ca2+ upon NMDA receptor-mediated synaptic activity (EC50 ∽ 2 pM) and potentiates NMDA responses. Inhibitor at GABAA receptors (IC50 values are 0.4 to >300 μM, depending on specific subunit conformation). Activates CREB phosphorylation, augments LTP and cognitive behavior in rat memory models. Also activates TRPM3 channels.
Specifications

Specifications

50 mg
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