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Invitrogen™ Predictor™ hERG Fluorescence Polarization Assay Kit
Predictor™ hERG Fluorescence Polarization Assay Kit
Brand: Invitrogen™ PV5365
This item is not returnable.
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Description
The Predictor™ hERG Fluorescence Polarization Assay Kit provides a set of validated components to perform hERG channel biochemical binding studies in the absence of radioligand. The assay was designed to identify potential hERG channel blockers by producing data that accurately correlates with patch-clamp electrophysiology studies. The assay is based on the principle of fluorescence polarization where a red-shifted fluorescent tracer is displaced from the hERG channel by compounds that bind to the channel. Assay performance was validated with a panel of established hERG channel blockers. Results from the Predictor™ assay demonstrate a high correlation with those obtained from patch clamp techniques.Specifications
Red | |
Fluorescence | |
1 Kit | |
PV5365 Predictor™ hERG Fluorescence Polarization Assay Kit |
|
Ion Channels | |
End Point | |
Predictor™ System | |
Predictor™ | |
Assay Kit |
Predictor hERG Tracer Red | |
Microplate Reader | |
384-well Plate | |
Biochemical binding | |
hERG | |
Dry Ice | |
hERG | |
Ion Channels |
For Research Use Only. Not for use in diagnostic procedures.