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PKC iota Mouse anti-Human, Mouse, Rat, Clone: 3A1B6, Proteintech

Mouse Monoclonal Antibody

1696.32 NOK - 4796.50 NOK

Specifications

Antigen PKC iota
Clone 3A1B6
Concentration 1 mg/mL
Applications Western Blot, Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16808425
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Proteintech
66493-1-IG-20UL
20 μL
1696.32 NOK
20µL
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16898415
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Proteintech
66493-1-IG-150UL
150 μL
4796.50 NOK
150µL
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Description

Description

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.
Specifications

Specifications

PKC iota
1 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
aPKC lambda/iota, DXS1179E, PKCI, PRKC lambda/iota, PRKCI, Protein kinase C iota type, protein kinase C, iota
Prkci
IgG2a
Protein A
Antibody
3A1B6
Western Blot, Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin)
Unconjugated
Mouse
Rat, Human, Mouse
F1M7Y5, P41743, Q62074
18759, 5584, 84006
PKC iota Fusion Protein Ag4990
Primary
-20°C
PRKCI
Videos
SDS
Documents

Documents

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