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Thermo Scientific™ Sulfo-SMCC (sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate), No-Weigh™ Format
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Quantity:
50 mg
10 x 2 mg
1 g
Unit Size:
1g
50mg
Pack of 10
Description
Thermo Scientific™ Pierce Sulfo-SMCC is a very popular, water-soluble, amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane spacer arm (8.3 Ås).
- Reactive groups: sulfo-NHS ester and maleimide
- Reactive towards: amino and sulfhydryl groups
- Water-soluble (compare to SMCC), so crosslinking can be done in physiologic solutions
- High purity, crystalline reagent can be used to create high-purity maleimide-activated derivatives
- Cyclohexane bridge confers added stability to the maleimide group making Sulfo-SMCC the ideal crosslinking agent for maleimide activation of proteins. Maleimide groups are stable for 64 hours in 0.1 M sodium phosphate buffer, pH 7 at 4°C.

Specifications
Specifications
Chemical Reactivity | Amine-Sulfhydryl |
Cleavable | No |
Description | Sulfo-SMCC |
Molecular Weight (g/mol) | 436.37 |
PEGylated | No |
Spacer Arm Length | 8.3 AĚŠ |
Content And Storage | Upon receipt store desiccated at -20°C. |
Cell Permeability | No |
Shipping Condition | Ambient |
Product Line | No-Weigh™ |
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Documents
Product Information
Manuals
User Guide: SMCC and Sulfo-SMCC
Version: C.0
File size: 172 kB
Certificates
Certificates
A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.
5 results found
Lot Number | Certificate Type | Date | Product Code |
---|---|---|---|
ZL408503 | Certificate of Analysis | 12/02/2025 | A39268 |
ZL402939 | Certificate of Analysis | 12/02/2025 | A39268 |
ZI396689 | Certificate of Analysis | 15/10/2024 | A39268 |
ZH396688 | Certificate of Analysis | 30/08/2024 | A39268 |
ZG394287 | Certificate of Analysis | 19/07/2024 | A39268 |
For Research Use Only. Not for use in diagnostic procedures.
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Product Title
Thermo Scientific™ Sulfo-SMCC (sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate), No-Weigh™ Format >
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