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Thermo Scientific™ Sulfo-LC-SPDP (sulfosuccinimidyl 6-(3'-(2-pyridyldithio)propionamido)hexanoate)

Crosslink amines to sulfhydryls with this water-soluble sulfo-NHS-ester and pyridyldithiol groups on 10-atom spacer arms to form cleavable disulfide bonds with cysteines.

Brand:  Thermo Scientific™ 21650

Regulatory: This product contains a substance listed in Annex XVII to REACH Regulation (EC) No 1907/2006, all customers must complete a declaration before delivery.

Product Code. 11801255

  • 6260.00 NOK / 50mg
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Description

Description

Thermo Scientific™ Pierce Sulfo-LC-SPDP is a water-soluble, long-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteines.

Highlights:

  • Forms cleavable disulfide bonds with sulfhydryls
  • Releases a detectable byproduct after reacting with free sulfhydryl groups; by measuring the release of pyridine-2-thione at 343nm, the reaction progression can be monitored
  • Reactive groups: sulfo-NHS ester and pyridyldisulfide
  • Reactive toward: amino and sulfhydryl groups
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Amine-Sulfhydryl
Sulfo-LC-SPDP
No
Upon receipt store at -20°C protected from moisture.
Ambient
Chemical Labeling
Pyridyldisulfide, Sulfo-NHS Ester
Powder
Water
Yes
By Thiols
527.57
15.7 Å
No
Pierce™
Heterobifunctional
Medium (10 to 30 Å)
50 mg
Standard
Crosslinker
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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberZI393048 Certificate TypeCertificate of Analysis Date12/02/2025 Catalog Number21650
Lot NumberYI376744 Certificate TypeCertificate of Analysis Date26/09/2023 Catalog Number21650
Lot NumberYB355448 Certificate TypeCertificate of Analysis Date10/08/2023 Catalog Number21650
Lot NumberYE360039 Certificate TypeCertificate of Analysis Date03/06/2023 Catalog Number21650
Lot NumberYA344430 Certificate TypeCertificate of Analysis Date27/01/2023 Catalog Number21650
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Product Title
Thermo Scientific™ Sulfo-LC-SPDP (sulfosuccinimidyl 6-(3'-(2-pyridyldithio)propionamido)hexanoate) > 50mg

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