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Thermo Scientific™ Sodium Deoxycholate Detergent
Water-soluble, ionic detergent used in cell lysis buffers (e.g., RIPA buffer) to disrupt protein interactions for liposome and membrane protein isolation.
Brand: Thermo Scientific™ 89905
This item is not returnable.
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Description
Thermo Scientific™ Sodium Deoxycholate is an ionic detergent that is especially useful for disrupting and dissociating protein interactions.
Sodium deoxycholate (deoxycholic acid) is a water-soluble, bile-acid, ionic detergent commonly used in protein methods. It is most frequently used as a component of cell lysis buffers (e.g., RIPA buffer) but also has been used for liposome preparation, isolation of membrane proteins and lipids, preventing nonspecific binding in affinity chromatography and a cell culture media supplement.Highlights:
- Popular anionic, bile-acid detergent for many laboratory uses
- Effective in disrupting and dissociating many types of protein interaction
- Can be removed from solution by dialysis
- Useful for elution or regeneration of certain kinds of affinity columns
- High-purity compound with low UV absorptivity
Detergent Properties:
- Alternative Names: Sodium deoxycholic acid; deoxycholate, sodium salt
- Chemical Name: 3, 12-α-Dihydroxy-5β-cholan-24-oic acid, monosodium salt
- Molecular Weight: 414.6
- Detergent Class: Ionic (anionic)
- Aggregation Number: 5 (average)
- Micelle Molecular Weight: 2000 (average)
- Critical Micelle Concentration (CMC): 2 to 6mM (0.083 to 0.249%, w/v)
- Cloud Point: Unknown
- Dialyzable: Yes
Specifications
| Detergent | |
| Powder | |
| 25 g |
| Store at -20°C | |
| Detergent (Pure) |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- Sodium Deoxycholate Detergent
Signal Word
- Warning
Hazard Category
- Acute toxicity Category 4
- Specific target organ toxicity Category 3
Hazard Statement
- H302-Harmful if swallowed.
- H335-May cause respiratory irritation.
Precautionary Statement
- P264-Wash hands thoroughly after handling.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P310-Immediately call a POISON CENTER/doctor/.
- P405-Store locked up.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Supplemental information
- MIXTURE LIST-Contains : sodium 3-droxy-5-oate
For Research Use Only. Not for use in diagnostic procedures.