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Thermo Scientific™ MS(PEG)4 Methyl-PEG-NHS-Ester Reagent
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Quantity:
100 mg
1 g
Unit Size:
100mg
1g
Description
Thermo Scientific™ Pierce MS(PEG)n reagents are methyl-terminated, polyethylene glycol compounds (n equals 4 to 24 PEG units) activated as NHS esters for covalent pegylation of primary amines on proteins (e.g., lysines) or assay surfaces.
MS(PEG)n is the abbreviation for a set of compounds having polyethylene glycol (PEG) spacers with methyl (—CH3) and amine-reactive NHS-ester groups at opposite ends. The unbranched, hydrophilic, discrete-length molecules have the form Methyl-PEGn-NHS Ester, where the subscript “n” denotes 4, 8, 12, or 24 ethylene glycol units. The N-hydroxysuccinimide (NHS) ester is spontaneously reactive with primary amines (—NH2), providing for efficient PEGylation of proteins, peptides and other amine-containing molecules or surfaces.
Highlights:
- NHS-activated for efficient PEGylation of primary amines at pH 7-9; reaction of NHS-ester group results in formation of stable, irreversible amide bonds
- Fully characterized PEGylation reagents with defined PEG chain lengths; molecules of discrete molecular weight for consistency of performance in protein-modification applications
- Provided as a series of 4, 8, 12 and 24 ethylene glycol units, enabling modification procedures to be optimized for a specific application while retaining all the benefits associated with protein PEGylation
- PEG spacer provides unique advantages, including increased stability, reduced tendency toward aggregation and reduced immunogenicity
- Easy-to-follow instructions increase the likelihood of a successful outcome

Specifications
Specifications
Chemical Reactivity | Amine |
Content And Storage | Store desiccated at -20°C. |
Label Type | Polyethylene Glycol (PEG), Blocking Groups |
Product Line | Pierce |
Reactive Moiety | Active Ester, Succinimidyl Ester, NHS Ester |
Spacer | 4 ethylene glycol units |
Form | Solid |
Quantity | 100 mg |
Solubility | Water |
Product Type | NHS-Ester Reagent |
Documents
Product Information
Manuals
User Guide: MS(PEG)n Reagents
Version: MAN0016373 Rev. A.0 (16Nov2016)
File size: 81.1 kB
Certificates
Certificates
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For Research Use Only. Not for use in diagnostic procedures.
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