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Thermo Scientific™ Pierce™ DSP, No-Weigh™ Format
Crosslink amines to amines with dithiobis succinimidyl propionate, composed of NHS-ester groups and disulfide-containing, 12.0A spacer arm and cleavable with reducing agents.
Brand: Thermo Scientific™ 22586
Product Code. 11821315
This item is not returnable.
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Description
Thermo Scientific™ Pierce DSP Crosslinker (Lomant's Reagent) is an amine-reactive crosslinker with NHS-ester reactive ends and a cleavable disulfide bond in its spacer arm.
Highlights:
- Cleavable by reducing agents
- Membrane-permeable
- Acylate in aqueous or organic media within two minutes at room temperature
- Four- to five-hour half-life of ester at pH 7.0
- Reactive groups: NHS ester (homobifunctional)
- Reactive toward: amino groups
Specifications
| Amine-Amine | |
| DSP | |
| No | |
| Upon receipt store desiccated at 4°C. | |
| Ambient | |
| Chemical Labeling | |
| NHS Ester | |
| Powder | |
| DMF, DMSO | |
| No |
| By Thiols | |
| 404.42 | |
| 12.0 Å | |
| Yes | |
| Pierce™ | |
| Homobifunctional | |
| Medium (10 to 30 Å) | |
| 50 mg | |
| Standard, Single-use, Premium-grade | |
| Crosslinker |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- DSP (dithiobis(succinimidyl propionate)), Lomant's Reagent
Signal Word
- Warning
Hazard Category
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
Hazard Statement
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
Precautionary Statement
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P264-Wash hands thoroughly after handling.
- P271-Use only outdoors or in a well-ventilated area.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P332+P313-If skin irritation occurs: Get medical advice/attention.
- P337+P313-If eye irritation persists: Get medical advice/attention.
- P403+P233-Store in a well-ventilated place. Keep container tightly closed.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Supplemental information
- MIXTURE LIST-Contains : disuccinimido dithiobispropionate
For Research Use Only. Not for use in diagnostic procedures.