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Thermo Scientific™ CT(PEG)12 Carboxy-PEG-Thiol Compound
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Thermo Scientific™ Pierce CT(PEG)12, or carboxy-PEG12-thiol, is a carboxyl- and sulfhydryl-terminated compound that contains a 12-unit polyethylene glycol (PEG) spacer and is used to modify surfaces such as quantum dots, monolayers and magnetic particles.
Highlights:
Metal-binding – terminal monodentate thiol reacts spontaneously with gold surfaces through dative binding
Carboxylate – terminal carboxylic acid group allows conjugation to amine-containing affinity ligands using carbodiimide (EDC) and Sulfo-NHS crosslinking chemistry
Polyethylene glycol – PEG groups are flexible, non-immunogenic, hydrophilic, and significantly reduce nonspecific binding of surfaces for protein methods
Spacer arm – 12-unit PEG spacer is nearly 48 angstroms long, minimizing steric hindrance for protein immobilization and binding assays
Specifications:
- Alternative name: Carboxy-PEG12-Thiol
- Chemical name: 1-mercapto-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxanonatriacontan-39-oic acid
- Chemical formula: C27H54O14S
- Molecular weight: 634.77
- Spacer arm: 47.8 angstroms
- Form: colorless to pale yellow liquid
- Solubility: dissolve in DMSO or DMF for use

Specifications
Specifications
Chemical Reactivity | Amine |
Content And Storage | Store at -20°C protected from moisture. Shipped at ambient temperature. |
Label Type | Conjugating Groups, Polyethylene Glycol (PEG) |
Reactive Moiety | Carboxylic Acid, Thiol |
Spacer | 12 ethylene glycol units |
Form | Solid |
Quantity | 100 mg |
Solubility | DMF or DMSO |
Product Type | Thiol Compound |
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