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Thermo Scientific™ Pierce™ Boronic Acid Resin Product Code.: 11836744

Thermo Scientific™ Pierce™ Boronic Acid Resin

Product Code. 11836744 Shop All Thermo Scientific Products
10 mL, 10mL
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Quantity:
10 mL
Unit Size:
10mL
This item is not returnable. View return policy

Product Code. 11836744

Brand: Thermo Scientific™ 20244

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This item is not returnable. View return policy

Selectively bind and remove or purify ribonucleotides and small oligonucleotide RNAs using polyacrylamide beads of immobilized m-aminophenyl-boronic acid.

Perform ribonucleotide and oligonucleotide RNA isolation with Thermo Scientific™ Pierce Boronic Acid Resin.

This immobilized boronic acid is an easy-to-use polyacrylamide affinity support for purification of ribonucleotides and other small molecular weight compounds that contain cis-diol groups. The ligand (m-aminophenyl-boronic acid) binds to the cis-diol groups on the sugar portion of nucleotides, forming a reversible five-member ring complex. After washing away non-bound molecules from the sample, the complex can be dissociated and the nucleotide eluted by lowering the pH or by addition of sorbitol.

Highlights:

  • Ligand – boronic acid

  • Support – beaded polyacrylamide (1800 MW exclusion limit)

  • Spacer – m-aminophenyl group

  • Loading – 100ÎĽmol boronate per milliliter of settled resin

  • Capacity – at least 99% binding and recovery of 110ÎĽmol AMP per milliliter of settled resin

  • Format – 50% resin slurry in 0.05% sodium azide

TRUSTED_SUSTAINABILITY

Specifications

Content And Storage Store at 4°C.
Form Resin Slurry
Product Line Pierce™
Quantity 10 mL
Target Ribonucleotide
Type Resin
Stationary Phase Boronic Acid
Format Bottle
Column Type Affinity, Polyacrylamide Resin

For Research Use Only. Not for use in diagnostic procedures.

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