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PICK1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1696.32 NOK - 4796.50 NOK

Specifications

Antigen PICK1
Concentration 0.13 mg/mL
Applications Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16847733
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Proteintech
10983-2-AP-20UL
20 μL
1696.32 NOK
20µL
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16837733
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Proteintech
10983-2-AP-150UL
150 μL
4796.50 NOK
150µL
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Description

Description

PSD-95/DLG/ZO-1 (PDZ) domain-containing proteins play a central role in synaptic membrane protein localization. The protein interacting with protein kinase C (PICK1) is a synaptic PDZ domain protein that also contains a coiled-coil and acidic domain. Studies indicate that PICK1 functions as a targeting and transport protein and has been shown to interact with protein kinase C alpha (PKCalpha), AMPA-type glutamate receptors, and several other membrane receptors via its PDZ domain. The interaction of PICK1 with PKCalpha is highly dependent on the activation of the kinase. It appears that PICK1 directs the activated form of PKCalpha to membrane anchored GluR2. Once phosphorylated by PKCalpha, GluR2 is released from the synaptic anchor proteins. Once released, GluR2 is transported from the synaptic membrane in a PICK1-dependent manner.
Specifications

Specifications

PICK1
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
Unconjugated
Rabbit
Mouse, Human, Rat
Q62083, Q9EP80, Q9NRD5
18693, 84591, 9463
PICK1 Fusion Protein Ag1443
Primary
-20°C
PICK1
0.13 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
PICK, PICK1, PRKCA binding protein, PRKCABP
Pick1
IgG
Antigen Affinity Chromatography
Antibody
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Documents

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