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PFI 1, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Potent BET bromodomain inhibitor; exhibits inhibitory activity at bromodomain-containing protein (BRD) 2 and BRD4 (IC50 values are 98 and 220 nM respectively). Induces apoptosis and G1 cell cycle arrest in BET inhibitor-sensitive cell lines (MV4;11). Also downregulates Aurora B expression in MV4;11 cells. Cell permeable.
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Specifications
Specifications
Quantity | 10 mg |
Formula Weight | 347.39 |
Percent Purity | >98% |
Chemical Name or Material | PFI 1 |
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