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PFI 1, Tocris Bioscience™

Product Code. 18094782
10 mg
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

BET bromodomain inhibitor

Potent BET bromodomain inhibitor; exhibits inhibitory activity at bromodomain-containing protein (BRD) 2 and BRD4 (IC50 values are 98 and 220 nM respectively). Induces apoptosis and G1 cell cycle arrest in BET inhibitor-sensitive cell lines (MV4;11). Also downregulates Aurora B expression in MV4;11 cells. Cell permeable.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1403764-72-6
Molecular Formula C16H17N3O4S
Molecular Weight (g/mol) 347.389
InChI Key TXZPMHLMPKIUGK-UHFFFAOYSA-N
Synonym pfi-1, 2-methoxy-n-3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl benzenesulfonamide, 2-methoxy-n-3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl benzene-1-sulfonamide, 2-methoxy-n-3-methyl-2-oxo-1,4-dihydroquinazolin-6-yl benzenesulfonamide, d03lnf, pfi 1, pfi hplc, 2-methoxy-n-3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl benzenesulfon amide
PubChem CID 71271629
IUPAC Name 2-methoxy-N-(3-methyl-2-oxo-1,4-dihydroquinazolin-6-yl)benzenesulfonamide
SMILES CN1CC2=C(C=CC(=C2)NS(=O)(=O)C3=CC=CC=C3OC)NC1=O

Specifications

Quantity 10 mg
Formula Weight 347.39
Percent Purity >98%
Chemical Name or Material PFI 1
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