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  7. N,N'-Disuccinimidyl carbonate, tech. 85%, remainder N-Hydroxysuccinimide, Thermo Scientific Chemicals

N,N'-Disuccinimidyl carbonate, tech. 85%, remainder N-Hydroxysuccinimide, Thermo Scientific Chemicals

Product Code. 11342509
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Quantity:
1 g
5 g
25 g
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Description

N,N'-Disuccinimidyl carbonate is used to prepare cleavable linker succinimide vinylsufonylethyl carbonate for thiol modified-DNA. It serves as a reagent for the synthesis of carbamates. Further, it is used as a coupling reagent as well as in the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate and coupling of ligand to proteins.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,N′-Disuccinimidyl carbonate is used to prepare cleavable linker succinimide vinylsufonylethyl carbonate for thiol modified-DNA. It serves as a reagent for the synthesis of carbamates. Further, it is used as a coupling reagent as well as in the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate and coupling of ligand to proteins.

Solubility
Soluble in dimethyl sulfoxide, hot pyridine, acetonitrile and most organic solvents. Insoluble in water.

Notes
Moisture sensitive. Store in a cool place. Incompatible with strong acids and oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 74124-79-1
Molecular Formula C9H8N2O7
Molecular Weight (g/mol) 256.17
MDL Number MFCD00009767
InChI Key PFYXSUNOLOJMDX-UHFFFAOYSA-N
Synonym n,n'-disuccinimidyl carbonate, bis 2,5-dioxopyrrolidin-1-yl carbonate, n,n'-disuccinimidylcarbonate, di succinimido carbonate, disuccinimidyl carbonate, di n-succinimidyl carbonate, n,n-disuccinimidyl carbonate, dsc, disuccinimido carbonate, pubchem12700
PubChem CID 676246
IUPAC Name bis(2,5-dioxopyrrolidin-1-yl) carbonate
SMILES C1CC(=O)N(C1=O)OC(=O)ON2C(=O)CCC2=O

Specifications

Melting Point 190°C (decomposition)
Quantity 1 g
Beilstein 1499137
Sensitivity Hygroscopic
Solubility Information Soluble in dimethyl sulfoxide,hot pyridine,acetonitrile and most organic solvents. Insoluble in water.
Formula Weight 256.17
Percent Purity 85%
Grade Technical
Assay remainder N-Hydroxysuccinimide
Chemical Name or Material N,N'-Disuccinimidyl carbonate

RUO – Research Use Only

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