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N-Hydroxysulfosuccinimide sodium salt, 97%, Thermo Scientific Chemicals Product Code.: 15469547
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N-Hydroxysulfosuccinimide sodium salt, 97%, Thermo Scientific Chemicals

Product Code. 15469547
1 g
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Quantity:
250 mg
1 g
5 g
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Product Code. 15469547

Brand: Thermo Scientific Alfa Aesar H52795.03

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Description

N-Hydroxysulfosuccinimide sodium salt is used as crosslinking agents for preparing hydrophilic active esters. It is also used to activate carboxylic acids to the more reactive succinimidyl esters for coupling, biotinylation and conjugation with fluorophores. Further, it acts as a hydrophilic ligand and also used in covalently binding proteins to carboxyl containing beads, resins, other nanoparticles. It is involved in the conversion of carboxyl groups to primary amine-reactive sulfo-NHS esters.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Hydroxysulfosuccinimide sodium salt is used as crosslinking agents for preparing hydrophilic active esters. It is also used to activate carboxylic acids to the more reactive succinimidyl esters for coupling, biotinylation and conjugation with fluorophores. Further, it acts as a hydrophilic ligand and also used in covalently binding proteins to carboxyl containing beads, resins, other nanoparticles. It is involved in the conversion of carboxyl groups to primary amine-reactive sulfo-NHS esters.

Solubility
Soluble in methanol and water.

Notes
Store in a cool place. Moisture sensitive. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 106627-54-7
Molecular Formula C4H4NNaO6S
Molecular Weight (g/mol) 217.127
MDL Number MFCD00043100
InChI Key RPENMORRBUTCPR-UHFFFAOYSA-M
Synonym n-hydroxysulfosuccinimide sodium salt, sulfo-nhs, sodium 1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate, n-hydroxysulfosuccinimidesodiumsalt, 3-pyrrolidinesulfonic acid, 1-hydroxy-2,5-dioxo-, monosodium salt, sodium 1-hydroxy-2,5-dioxo-pyrrolidine-3-sulfonate, n-hydroxusulfosuccinimide sodium, n-hydroxy-2-sodiosulfo succinimide, n-hydroxysulfosuccinimide,sodium salt, n-hydroxusulfosuccinimide sodium saltShow MoreShow Less
PubChem CID 3520574
IUPAC Name sodium;1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate
SMILES C1C(C(=O)N(C1=O)O)S(=O)(=O)[O-].[Na+]

Specifications

Melting Point 250°C
Quantity 1 g
Beilstein 6359129
Solubility Information Soluble in methanol and water.
Formula Weight 217.13
Percent Purity 97%
Chemical Name or Material N-Hydroxysulfosuccinimide sodium salt

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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberX07H047 Certificate TypeCertificate of Analysis Date06/09/2024 Catalog NumberH52795.03,H52795.MD,H52795.06
Lot Number10234924 Certificate TypeCertificate of Analysis Date06/09/2024 Catalog NumberH52795.03,H52795.MD,H52795.06
Lot NumberT12I026 Certificate TypeCertificate of Analysis Date22/07/2022 Catalog NumberH52795.03,H52795.MD,H52795.06
Lot NumberT07D039 Certificate TypeCertificate of Analysis Date07/12/2021 Catalog NumberH52795.03,H52795.MD,H52795.06
Lot NumberB23X011 Certificate TypeCertificate of Analysis Date07/12/2021 Catalog NumberH52795.03,H52795.MD,H52795.06

Safety and Handling

compliance-icons
Product Identifier
  • N-Hydroxysulfosuccinimide sodium salt
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
 Supplemental information
  • MIXTURE LIST-Contains : N-Hydroxysulfosuccinimide sodium salt
SDS

RUO – Research Use Only

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