Learn More
Invitrogen™ MTCH2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA588873
Description
Immunogen sequence: VGYEPLPPTI GRNIFGRQVC QLPGLFSYAQ HIASIDGRRG LFTGLTPRLC SGVLGTVVHG KVLQHYQESD KGEELGPGNV QKEVSSSFDH VIKETTREMI ARSAATLITH PFHVITLRSM VQFIGRESKY CGLCDSIITI YREEGI; Positive Samples: HepG2, HeLa, 293T, HT-29, Mouse small intestine, Mouse brain, Mouse liver; Cellular Location: Mitochondrion inner membrane, Multi-pass membrane protein.
MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death.
Specifications
MTCH2 | |
Polyclonal | |
Unconjugated | |
Mtch2 | |
2310034D24Rik; 4930539J07Rik; HSPC032; Met-induced mitochondrial protein; MIMP; mitochondrial carrier 2; mitochondrial carrier homolog 2; mitochondrial carrier homolog 2 (C. elegans); Mtch2; SLC25A50; solute carrier family 25, member 50 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
23788, 56428 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.2 mg/mL | |
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
Q791V5, Q9Y6C9 | |
Mtch2 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-175 of human MTCH2 (NP_0551571). | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Your input is important to us. Please complete this form to provide feedback related to the content on this product.