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Invitrogen™ Rhodamine 110, bis-(p-Tosyl-L-Glycyl-L-Prolyl-L-Arginine Amide)

This Molecular Probes™ bisamide derivative of rhodamine 110 (R110) is a sensitive and selective substrate for assaying proteases in solution or inside living cells.

Brand:  Invitrogen™ R22124

4324.40 NOK valid until 2025-04-18
Use promo code "24107" to get your promotional price.

Product Code. 10124292

  • 5750.00 NOK / Each

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Description

Description

This Molecular Probes™ bisamide derivative of rhodamine 110 (R110) is a sensitive and selective substrate for assaying proteases in solution or inside living cells. These fluorogenic substrates contain an amino acid or peptide covalently linked to each of R110's amino groups. Upon enzymatic cleavage, the nonfluorescent bisamide substrate is converted first to the fluorescent monoamide and then to R110, with a further increase in fluorescence. The substrate can be used to continuously measure enzyme activity in cell extracts and purified enzyme preparations using a fluorometer or fluorescence microplate reader, or can be used for intracellular protease assays with analysis by flow cytometry or fluorescence microscopy.<

• Has spectral properties similar to those of fluorescein, making it compatible with standard fluorescein filter sets
• Signal to background ratios are good because of large extinction coefficient of R110
• Unlike fluorescein, the fluorescence intensity of the rhodamine 110 reaction product is constant from pH 3–9
• Substrate name: p-tosyl-Gly-Pro-Arg)2-R110
• Useful to measure: Thrombin
• Ex/Em of R110 product: (498/521nm)
• Cell-Permeant

Order Info

Shipping Condition: Room temperature

TRUSTED_SUSTAINABILITY
Specifications

Specifications

Cell-Permeant
Fluorescence
2 mg
Peptide-Based Substrate
Fluorometer, Microplate Reader
Store in freezer (-5 to -30°C).
Solid
Caspase Substrate
Thrombin
Room Temperature
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Manuals

Rhodamine 110-Based Proteinase Substrates Version: 01-11-2006 File size: 133.6 kB
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5 results found
Lot Number Certificate Type Date Catalog Number
Lot Number2790111 Certificate TypeCertificate of Analysis Date11/03/2024 Catalog NumberR22124
Lot Number2738285 Certificate TypeCertificate of Analysis Date26/10/2023 Catalog NumberR22124
Lot Number2696826 Certificate TypeCertificate of Analysis Date16/06/2023 Catalog NumberR22124
Lot Number2595612 Certificate TypeCertificate of Analysis Date16/02/2023 Catalog NumberR22124
Lot Number2015680 Certificate TypeCertificate of Analysis Date15/09/2018 Catalog NumberR22124
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Product Title
Invitrogen™ Rhodamine 110, bis-(p-Tosyl-L-Glycyl-L-Prolyl-L-Arginine Amide) > 2mg

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