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Tocris Bioscience™ ML 162

Inhibits glutathione peroxidase (GPX4); induces ferroptosis

Brand: Tocris Bioscience™ 7821/50

6064.64 NOK valid until 2024-12-16
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Product Code. 30000010

7665.00 NOK / 50mg

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Description

ML 162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor. It induces ferroptosis in vivo. It is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50 = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively).

Specifications

Chemical Name or Material	2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide
Quantity	50 mg
Molecular Formula	C₂₃H₂₂Cl₂N₂O₃S

CAS	1035072-16-2
Target	Glutathione Peroxidase 4/GPX4
Purity	0.98

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