missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Unclassified Organic Compounds
  6. ML 120B dihydrochloride, Tocris Bioscience™
  • missing translation for 'structureSearchLink'
  • Print

ML 120B dihydrochloride, Tocris Bioscience™

Product Code. 30002045
missing translation for 'orderingAttributeHoverText'
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Novel IKK2-selective inhibitor

Novel, ATP-competitive IKK2-selective inhibitor (IC50 = 60 nM at 50 μM ATP). Exhibits no inhibition at IKK1 (EC50 >100 μM), IKKε (EC50 >100 μM) or a panel of 28 other kinases (EC50 >50 μM). Exhibits antitumor activity in lymphoma-bearing SCID mice. Demonstrates synergistic cytotoxic effects with vincristine (Cat. No. 1257).

Chemical Identifiers

CAS 783348-36-7
Molecular Formula C19H15ClN4O2
Molecular Weight (g/mol) 366.81
InChI Key ZNOLRTPMNMPLHY-UHFFFAOYSA-N
Synonym mln120b, mln-120b, n-6-chloro-7-methoxy-9h-pyrido 3,4-b indol-8-yl-2-methylnicotinamide, ml 120b dihydrochloride, n-6-chloro-7-methoxy-9h-pyrido 3,4-b indol-8-yl-2-methyl-3-pyridinecarboxamide, d0t8is, mln 120b, znolrtpmnmplhy-uhfffaoysa-n, n-6-chloro-7-methoxy-9h-beta-carbolin-8-yl-2-methyl-nicotinamide, n-6-chloro-7-methoxy-9h-beta-carbolin-8-yl-2-methylnicotinamide
PubChem CID 9929127

Specifications

Quantity 50 mg
Formula Weight 439.72
Chemical Name or Material ML 120B dihydrochloride
missing translation for 'provideContentCorrection'

missing translation for 'productTitle'

missing translation for 'byClickingSubmit' missing translation for 'privacyPolicy'.