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Metformin hydrochloride, Tocris Bioscience™
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Quantity:
100 mg
Description
Metformin hydrochloride is an antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines via inhibition of mitochondrial complex I (MRC-1). Activates the aPKC-CBP pathway in neural precursors to promote neurogenesis. Activates autophagy. Identified by chemoinformatics as targeting human host proteins that interact with SARS-CoV-2.
Specifications
Specifications
CAS | 1115-70-4 |
Molecular Formula | C4H12ClN5 |
MDL Number | MFCD00012582 |
Quantity | 100 mg |
Synonym | metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform |
InChI Key | OETHQSJEHLVLGH-UHFFFAOYSA-N |
SMILES | [H+].[Cl-].CN(C)C(=N)N=C(N)N |
IUPAC Name | hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride |
Molecular Weight (g/mol) | 165.63 |
PubChem CID | 14219 |
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